Epidemiología de la apendicitis aguda en Colombia: Un análisis de las bases de datos administrativas del Ministerio de Salud / Epidemiology of acute appendicitis in Colombia: An Analysis of the Ministry of Health administrative databases

Introducción. La apendicitis aguda es una afección común, con un pico de incidencia entre los 10 y 20 años. La cirugía es el tratamiento preferido y la apendicectomía por laparotomía sigue siendo el estándar, aunque el abordaje laparoscópico ha mostrado menos complicaciones. El objetivo de este artículo fue caracterizar tanto la enfermedad como el tratamiento quirúrgico en Colombia, usando datos de bases oficiales. Métodos. Se accedió a la base de datos del Sistema Integrado de Información para la Protección Social (SISPRO) del Ministerio de Salud de Colombia en febrero de 2023. Se recogieron datos de los pacientes con diagnóstico de apendicitis y con procedimiento de apendicectomía entre 2017 y 2021, y se analizaron por edad, sexo y ubicación geográfica. Resultados. Entre 2017 y 2021 se diagnosticaron 345.618 casos de apendicitis (51,8 % mujeres), con pico de incidencia a los 15-20 años. Se realizaron 248.133 apendicectomías, el 16,7 % por laparoscopia. Los hospitales con más procedimientos reportados estaban en Bogotá, Yopal, Popayán y Florencia. La mortalidad fue de 0,56 % en hombres y 0,51 % en mujeres. Conclusión. La apendicitis es común, con pico a los 10-19 años. Las mujeres tienen mayor probabilidad de apendicectomía, debido a otras afecciones ginecológicas. El acceso a la apendicectomía disminuye la mortalidad; en estos pacientes, el 16 % fue laparoscópica, lo que sugiere que se necesita más entrenamiento y acceso a esta técnica. Este estudio aporta a la comprensión de la epidemiología de la apendicitis y apendicectomías en Colombia.

Introduction. Acute appendicitis is a common condition, with a peak incidence between 10 and 20 years of age. Surgery is the preferred treatment and laparotomy appendectomy remains the standard, although the laparoscopic approach has shown fewer complications. The objective of this article was to characterize both the disease and the surgical treatment in Colombia, using data from official databases. Methods. The Integrated Information System for Social Protection (SISPRO) database of the Ministry of Health was accessed in February 2023. Data with diagnosis of apendicitis and with appendectomy between 2017 and 2021 were collected. Analysis was done by age, gender, and geographic location. Results. Between 2017 and 2021, 345,618 cases of appendicitis were diagnosed (51.8% females), with peak incidence at 15-20 years of age. A total of 248,133 appendectomies were performed, 16.7% by laparoscopy. The hospitals with most reported procedures were located in Bogotá, Yopal, Popayán, and Florencia. Mortality was 0.56% in men and 0.51% in women. Conclusion. Appendicitis is common, peaking at ages 10-19. Women are more likely undergo appendectomy due to other gynecological conditions. Access to appendectomy improves mortality. In these patients, 16% were laparoscopic, suggesting that more training and access to this technique is needed. This study contributes to the understanding of the epidemiology of appendicitis and appendectomies in Colombia.

Apendectomía Convencional vs. Laparoscópica en pasantes de cirugía general / Conventional Vs Laparoscopic Appendectomy in General Surgery Interns

La apendicitis aguda (AA) es una de las afecciones más frecuentes para la consulta por el servicio de guardia que requiere tratamiento quirúrgico, con una incidencia estimada de entre 6 y 8%. Métodos: Se crearon dos grupos compuestos por 25 pacientes seleccionados al azar: G1. Apendectomía laparoscópica (AL). G2. Apendectomía convencional (CA). Analizamos variables como sexo, edad, tiempo de operación, dolor postoperatorio, estadía en el hospital y complicaciones postoperatorias. Resultados: el 53.2% de los pacientes eran hombres y el 46.8% restante eran mujeres, con una edad media de 31 años. La serie arrojó una tasa de complicación general del 28% para G1 y 68% para G2. Conclusión: lo que marca la evolución no es solo la capacidad del residente interino, sino también la condición del órgano y los propios factores del paciente

Acute appendicitis (AA) is one of the most frequent conditions for consultation by the on-call service that requires surgical treatment, with an estimated incidence of between 6 and 8%. Methods: Two groups made up of 25 randomly selected patients were created: G1. Laparoscopic appendectomy (AL). G2. Conventional appendectomy (CA). We analyzed variables such as sex, age, operating time, postoperative pain, hospital stay, and postoperative complications. Results: 53.2% of the patients were male and the remaining 46.8% were female, with a mean age of 31 years. The series yielded a general complication rate of 28% for G1 and 68% for G2. Conclusión: What marks the evolution is not only the capacity of the acting resident, but also the condition of the organ and the patient's own factors

Intususcepción intestinal en el contexto de una apendicitis aguda / Intestinal intussusception in the context of acute appendicitis: a case report and lit-erature review

Introducción: La intususcepción es una patología abdominal idiopá-tica o secundaria a procesos intesti-nales que actúan como puntos de partida para la invaginación. Se han descrito casos de arrastre de estruc-turas que derivan en otros procesos inflamatorios como la apendicitis aguda. Caso clínico: Niño 3 años, con dolor abdominal de 6 horas de evolución. Al examen físico se pre-senta pálido, somnoliento, taqui-cárdico y deshidratado. El abdo-men con signos apendiculares posi-tivos, con palpación en masa en fosa iliaca derecha. Taller diagnóstico: Leucocitos 9690 u/mm3, neutrófilos 58.1%. Ecografía con imagen sugerente de intususcepción intestinal con cam-bios inflamatorios en la grasa me-sentérica. Se realiza tomografía abdominal que reporta intususcep-ción ileocolónica de 47 x 50 mm, con múltiples ganglios reactivos mesentéricos, con imagen apendicu-lar en dirección pélvica, con apendi-colito en su interior. Evolución: El manejo quirúrgico incluyó una laparotomía explorato-ria con desinvaginación manual y apendicectomía convencional. El reporte de patología fue apendicitis aguda supurativa. El paciente 48 horas hospitalizado, recibió Ampici-lina + Sulbactam y analgesia. Al mejorar la función abdominal fue dado de alta. Conclusiones: En este caso la apendicitis aguda fue la causa de intususección intestinal con el signo ecográfico de la "diana" en un paciente de 3 años de edad.

Introduction: Intussusception is an idiopathic abdominal pathology or secondary to intestinal processes that act as starting points for intussusception. Cases of dragging of structures that lead to other inflammatory processes, such as acute appendicitis, have been described. Clinical case: 3-year-old boy with abdominal pain of 6 hours of evolution. On physical examination, he appears pale, drowsy, tachycardic, and dehydrated. The abdomen with positive appendiceal signs, with palpation of a mass in the right iliac fossa. Diagnostic workshop: leukocytes 9690 u/mm3, neutrophils 58.1%. Ultrasound with image suggestive of intestinal intussusception with inflammatory changes in the mesenteric fat. An abdominal tomography was performed that reported ileocolonic intussusception of 47 x 50 mm, with multiple mesenteric reactive nodes, an appendicular image in the pelvic direction, and an appendicolith inside. Evolution: Surgical management included an exploratory laparotomy with manual evagination and conventional appendectomy. The pathology report was acute suppurative appendicitis. The patient was hospitalized for 48 hours and received Ampicillin + Sulbac-tam and analgesia. When abdominal function improved, he was discharged. Conclusions: In this case, acute appendicitis was the cause of intestinal intussusception with the ultrasound sign of the "target" in a 3-year-old patient.

Apendicetomía electiva: caso clínico y revisión de la bibliografía / Elective appendectomy: clinical case and literature review / Apendectomia eletiva: caso clínico e revisão da literatura

Las masas inflamatorias de origen apendicular son cuadros de presentación poco frecuente, el 3 % de las apendicitis agudas. Su manejo terapéutico puede ser sistematizado en cirugía de inicio o tratamiento conservador. Este último consiste en antibioticoterapia exclusiva, o asociada al drenaje percutáneo. Es una alternativa frente a emprender una apendicectomía demandante, con riesgo de no identificar el apéndice cecal, lesión visceral y necesidad de conversión o resecciones extendidas. Sin embargo, en estos pacientes, la ausencia de la confirmación diagnóstica anatomo-patológica obliga a un seguimiento protocolizado a fin de descartar diagnósticos diferenciales de mayor relevancia pronóstica. Objetivo: Presentar el caso de un paciente en el que se realizó manejo conservador y apendicetomía electiva. Se realizó una revisión bibliográfica de las pautas de seguimiento e indicación de la apendicectomía electiva. Discusión y conclusiones: Las masas inflamatorias de origen apendicular representan un desafío diagnóstico y terapéutico, requiriendo un manejo y seguimiento específico. La indicación de apendicectomía electiva es controversial, es planteable frente a la persistencia de imágenes patológicas y dudas diagnósticas, o en pacientes con apendicitis recurrentes.

Inflammatory masses of appendiceal origin are infrequent; represent 3 % of acute appendicitis. Its therapeutic management can be systematized in initial surgery or conservative treatment. The latter consists of exclusive antibiotic therapy, or associated with percutaneous drainage. it is an alternative to undertaking a demanding appendectomy, with the risk of not identifying the cecal appendix, visceral injury, and the need for conversion or extended resections. However, the absence of pathological diagnostic confirmation requires protocolized follow-up in order to rule out differential diagnoses of greater prognostic relevance. Objective: present the case of a patient who underwent conservative management and elective appendectomy. a bibliographic review was carried out in the databases: pubmed, cochrane library, scielo and lilacs. Discussion and conclusions: inflammatory masses of appendiceal origin represent a diagnostic and therapeutic challenge, requiring specific management and follow-up. The indication for elective appendectomy is controversial, it is considered in the presence of persistent pathological images and diagnostic doubts, or in patients with recurrent appendicitis.

Massas inflamatórias de origem apendicular são quadros de apresentação pouco frequentes, 3 % de as apendicites agudas. seu manejo terapêutico pode ser sistematizado em cirurgia inicial ou tratamento conservador. esta última consiste na antibioticoterapia exclusiva, ou associada à drenagem percutânea. é uma alternativa à realização de uma apendicectomia exigente, com risco de não identificação do apêndice cecal, lesão visceral e necessidade de conversão ou ressecções extensas. no entanto, nesses pacientes, a ausência de confirmação diagnóstica patológica requer acompanhamento protocolarizado para afastar diagnósticos diferenciais de maior relevância prognóstica. Objetivo: apresentar o caso de um paciente submetido a tratamento conservador e apendicectomia eletiva. foi realizada revisão bibliográfica nas bases de dados: pubmed, biblioteca cochrane, scielo e lilacs. Discussão e conclusões: as massas inflamatórias de origem apendicular representam um desafio diagnóstico e terapêutico, exigindo manejo e seguimento específicos. a indicação de apendicectomia eletiva é controversa, sendo considerada na presença de imagens patológicas persistentes e dúvidas diagnósticas, ou em pacientes com apendicite recorrente.

Comparing financing models for supplementary healthcare in appendectomy: activity-based costing (fee-for-service) vs. diagnosis related group remuneration (bundled payment): a systematic review and meta-analysis

Purpose: In Brazil, healthcare services traditionally follow a fee-for-service (FFS) payment system, in which each medical procedure incurs a separate charge. An alternative reimbursement with the aim of reducing costs is diagnosis related group (DRG) remuneration, in which all patient care is covered by a fixed amount. This work aimed to perform a systematic review followed by meta-analysis to assess the effectiveness of the Budled Payment for Care Improvement (BPCI) versus FFS. Methods: Our work was performed following the items of the PRISMA report. We included only observational trials, and the primary outcome assessed was the effectiveness of FFS and DRG in appendectomy considering complications. We also assessed the costs and length of hospital stay. Meta-analysis was performed with Rev Man version 5.4. Results: Out of 735 initially identified articles, six met the eligibility criteria. We demonstrated a shorter hospital stay associated with the DRG model (mean difference = 0.39; 95% confidence interval ­ 95%CI ­ 0.38­0.40; p < 0.00001; I2 = 0%), however the hospital readmission rate was higher in this model (odds ratio = 1.57; 95%CI 1.02­2.44, p = 0.04; I2 = 90%). Conclusions: This study reveals a potential decrease in the length of stay for appendectomy patients using the DRG approach. However, no significant differences were observed in other outcomes analysis between the two approaches.

Survival rate, recurrence rate, and complications of routine appendectomy for patients with borderline and malignant mucinous ovarian tumor: A systematic review and meta-analysis / Philippine Journal of Obstetrics and Gynecology

Objective@#The objective of the study is to determine the survival rate, recurrence rate, and complication rate among patients diagnosed with borderline and malignant mucinous ovarian tumor (MOT) who underwent complete surgical staging with appendectomy.@*Methodology@#Eligibility criteria – A search of published literature was conducted in the electronic databases of MEDLINE (PubMed), Cochrane, and Google Scholar through 2000–2022, using a search strategy based on the PIO framework. Information of sources – The citations were identified with the use of a combination of the following text words: “mucinous ovarian tumors,” “MOT,” “appendectomy,” and “pseudomyxoma peritonei.” All retrospective studies with histopathologic diagnosis of borderline or malignant MOTs with patients who underwent appendectomy during primary surgery, including encompassing data on survival rate, recurrence rate, and/or incidence of complications (postoperative infections, appendectomy site leakage, hemorrhage, abscess, peritonitis, bowel perforation, and intestinal obstruction) that matched the terms set by the researchers were retrieved. Risk of bias – For the methodological quality of the individual clinical trials, the Jadad scale was used, which is based on the three following subscales: randomization (2, 1, or 0), blinding (2, 1, or 0), and dropouts/withdrawals (1 or 0). Guidelines for Cochrane collaboration were used to assess the risk bias. Synthesis of results – Review Manager version 5.3 (RevMan 5.4.1) was used by the researcher to perform the systematic review and meta-analysis of included studies.@*Results@#There were eight retrospective studies included in this study. The random interval for survival rate is 64.9%–99.7% with a P < 0.1. The prediction interval for recurrence rate is 0%–100% with 95% confidence interval. The odds of complications occurring are <0.69–2.99 times with 95% confidence interval, with mean effect size is 0.083, and with a 95% confidence interval is 0.027–0.23.@*Conclusion@#The mean prevalence of abnormal histology of the appendix in patients diagnosed with borderline and malignant MOTs and underwent appendectomy during primary surgery is 3%–13%. There is no statistically significant difference in survival rate of patients who were diagnosed with borderline and malignant MOTs with or without appendectomy during primary surgery. The prediction interval for recurrence rate is 0%–100% with 95% confidence interval. There is no significant difference between the rate of complications in patients who underwent appendectomy and those without.

Trombosis de vena mesentérica superior como complicación de apendicitis aguda: una entidad poco frecuente / Superior mesenteric vein thrombosis as a complication of acute appendicitis: a rare entity

Las complicaciones de la apendicitis aguda ha sido ampliamente descrita en la literatura; la trombosis venosa mesenterica es una manifestación poco común de esta patologia correspondiento a menos del 1 % de frecuencia, esto puede desorientar al cirujano general al coexistir en el cuadro de apendicitis aguda. Presentamos el caso de un paciente masculino de 58 años, con dolor abdominal de 5 días de evolución, con sintomatologia poco especifica para el diagnóstico concreto de apendicitis. Se realizó una tomografía computarizada de abdomen con hallazgos de apendicitis aguda y trombososis venosa mesenterica con un coágulo de 11.5 cm. Se hizó también apendicectomia abierta y se inició anticoagulación al egreso hospitalario.

The complications of acute appendicitis have been widely described in the literature; Mesenteric venous thrombosis is a rare manifestation of this pathology corresponding to less than 1% frequency, this can confuse the general surgeon as it coexists with acute appendicitis. We present the case of a 58-year-old male patient, with abdominal pain of 5 days of evolution, with symptoms that are not very specific for the specific diagnosis of appendicitis. Computed tomography of the abdomen was performed with findings of acute appendicitis and mesenteric venous thrombosis with a clot of 11.5 cm. An open appendectomy was performed and anticoagulation was started on hospital discharge.

Procedimiento de malone videoasistido en pediatria: primeros dos casos en Uruguay / Laparoscopic malone procedure in pediatrics: first cases in Uruguay / Procedimento de malone videoassistido em pediatria: dois primeiros casos no Uruguai

El procedimiento de apendicostomía continente para la realización de enemas anterógrados ha sido publicado ya hace varios años para el tratamiento de la incontinencia fecal y del estreñimiento de muy difícil manejo. Otra indicación del mismo incluye el estreñimiento severo, en el cual se agotaron las medidas farmacológicas y el único tratamiento efectivo es la realización de enemas. El objetivo principal del procedimiento es ofrecer a los niños y sus familias una alternativa a la hora de realizar los enemas, logrando una mayor adherencia al tratamiento y buscando alcanzar una mejor calidad de vida que permita adecuarse a las actividades con sus pares. Por otra parte permite al niño ir logrando cierta independencia gradual a medida que crezca, preparándolos para el futuro y haciéndolos participes activos de su cuidado. Se describen los primeros casos en donde utilizamos en nuestro medio el abordaje laparoscópico, sus indicaciones, la técnica quirúrgica y los resultados iniciales. Hemos constatado como ventaja principal los beneficios del abordaje mínimamente invasivo, como la exploración completa de la cavidad abdominal, el menor dolor postoperatorio, cicatrices más pequeñas, menor creación de adherencias.

The appendicostomy procedure for performing antegrade enemas has been published several years ago for the treatment of fecal incontinence and constipation that are very difficult to manage. The Malone procedure is performed in our setting, especially in patients with fecal incontinence secondary to neurological disorders such as myelomeningocele using a conventional approach. Other indications of it is severe constipation, in which pharmacological measures have been exhausted and the only effective treatment is enemas. The main objective of the procedure is to offer children and their families an alternative when performing enemas, achieving greater adherence to treatment and seeking to achieve a better quality of life that allows them to adapt to the activities of their peers. On the other hand, it allows the child to achieve a certain gradual independence as they grow, preparing them for the future and making them active participants in their care. The first cases in which we use the laparoscopic approach, its indications, the surgical technique and the initial results are described. We think that its main advantage is the benefits of the minimally invasive approach, such as complete exploration of the abdominal cavity, less postoperative pain, smaller scars, and less creation of adhesions.

O procedimento de apendicostomia continente para a realização de enemas anterógrados foi publicado há vários anos para o tratamento de incontinência fecal e constipação de difícil manejo. Outra indicação inclui constipação grave, na qual as medidas farmacológicas foram esgotadas e o único tratamento eficaz são os enemas. O principal objetivo do procedimento é oferecer às crianças e seus familiares uma alternativa na realização dos enemas, alcançando maior adesão ao tratamento e buscando alcançar uma melhor qualidade de vida que lhes permita adaptar-se às atividades com seus pares. Por outro lado, permite que a criança alcance uma certa independência gradual à medida que cresce, preparando-a para o futuro e tornando-a participante ativa em seus cuidados. São descritos os primeiros casos em que utilizamos a via laparoscópica, suas indicações, a técnica cirúrgica e os resultados iniciais. Confirmamos os benefícios da abordagem minimamente invasiva como principal vantagem, como exploração completa da cavidade abdominal, menos dor pós-operatória, cicatrizes menores e menor formação de aderências.

Apendicitis aguda y el riesgo de tumor maligno oculto. Presentación de un caso y revisión sistemática de la literatura / Acute appendicitis and the risk of hidden malignant tumor. Presentation of a case and systematic review of literature

Introducción: Los tumores apendiculares representan aproximadamente 1% de los tumores malignos del intestino grueso. Más del 50% de las neoplasias primarias del apéndice se manifiestan inicialmente como apendicitis aguda. Métodos: Se reporta caso de paciente masculino que presentó adenocarcinoma invasor en biopsia de pieza quirúrgica de apéndice cecal tras apendicectomía, tomando la decisión de realizar hemicolectomía derecha laparoscópica diferida. Discusión: En este caso y como en la mayoría de los reportes de la bibliografía mundial, el adenocarcinoma simula un cuadro de AA. En un metaanálisis y una revisión sistemática de 2.771 pacientes diagnosticados de masa apendicular inflamatoria (flemón o absceso), Andersson et al. encontró 31 con tumores malignos. Estas lesiones se detectan en el 0,9% al 1,4% de las apendicectomías realizadas para tratar la AA. Conclusión: Este subtipo histológico presenta mayor incidencia de metástasis en los ganglios linfáticos y la supervivencia global era del 47,5%. Es por ello por lo que abogamos por la resección colónica como tratamiento definitivo del adenocarcinoma de apéndice cecal.

INTRODUCTION: Appendulular tumors represent approximately 1% of malignant tumors of the large intestine. More than 50% of the primary neoplasms of the appendix initially manifest as acute appendicitis. Methods: Men's patient who presented invading adenocarcinoma in Cecal Appendix Surgical Party Biopsy after appendectomy, making the decision to perform deferred laparoscopic right hemicolectomy, is reported. Discussion: In this case and as in most world literature reports, adenocarcinoma simulates an AA picture. In a meta -analysis and a systematic review of 2,771 diagnosed patients of inflammatory appendicular mass (phlegmon or abscess), Andersson et al. He found 31 with malignant tumors. These lesions are detected at 0.9% to 1.4% of appendectomies made to treat the AA. Conclusion: This histological subtype has a greater incidence of metastasis in lymph nodes and global survival was 47.5%. That is why we advocate colonic resection as a definitive treatment of cecal appendix adenocarcinoma.

Apendicitis aguda durante la pandemia de COVID-19: experiencia en un centro de alta complejidad en Boyacá, Colombia / Acute appendicitis during the COVID-19 pandemic: Experience in a high-level complex center in Boyacá, Colombia

Introducción. La pandemia de COVID-19 replanteó la forma de atención en los sistemas de salud, afectando todas aquellas patologías no relacionadas con infecciones respiratorias, como la apendicitis aguda. El miedo al contagio por SARS-CoV-2 y las medidas restrictivas a la movilidad pudieron aumentar el tiempo desde el inicio de los síntomas hasta la consulta al servicio de urgencias, derivando en complicaciones intra y posoperatorias. Métodos. Estudio observacional descriptivo de corte trasversal y retrospectivo, donde se incluyeron todos los pacientes diagnosticados con apendicitis aguda llevados a apendicectomía, que fueron divididos en dos grupos, considerados prepandemia, desde el 1° de septiembre de 2018 al 15 de marzo de 2020, y pandemia, desde el 16 de marzo de 2020 al 30 de septiembre de 2021. Resultados. Fueron identificados 1000 pacientes, distribuidos en 501 pacientes en el grupo prepandemia y 499 en el grupo pandemia. El promedio de tiempo de consulta desde el momento de inicio de síntomas hasta consulta fue de 43 horas en el grupo prepandemia y de casi 45 horas en el grupo pandemia. Discusión. A pesar de las restricciones por la enfermedad causada por el nuevo coronavirus y el miedo que puede existir por el contagio, en nuestro centro no se evidenció un cambio en el manejo y presentación de los pacientes diagnosticados con apendicitis aguda

Introduction. The COVID-19 pandemic varied the way health systems were attended, thus affecting pathologies not related to respiratory infections, such as acute appendicitis. Fear of SARS-CoV-2 infection and mobility restrictive measures may have implied a longer time from the onset of symptoms to consultation of the emergency department, leading to intraoperative and postoperative complications. Methods. Retrospective cross-sectional descriptive observational study, identifying all patients diagnosed with acute appendicitis and taken for appendectomy, divided into two groups, considered pre-pandemic, from September 1, 2018 to March 15, 2020, and pandemic, from March 16, 2020 to September 30, 2021. Results. One-thousand patients were identified, 501 patients were distributed in the pre-pandemic group and 499 in the pandemic group. The average consultation time from the time of onset of symptoms to consultation was 43 hours in the prepandemic group and almost 45 hours in the pandemic. Discussion. Despite the restrictions due to the disease caused by the new coronavirus and the fear that may existed due to contagion, in our center there was no evidence of a change in the management and presentation of patients diagnosed with acute appendicitis

Comparación de la seguridad y la eficacia del uso de antibióticos frente a la apendicectomía en el tratamiento de la apendicitis no complicada en adultos. Revisión sistemática y metaanálisis / Comparison of safety and effectiveness of the use of antibiotics versus appendectomy in the management of uncomplicated appendicitis in adults. Systematic review and metanalysis

Introducción. La apendicitis aguda es una emergencia quirúrgica frecuente, en la cual el tratamiento de tipo conservador basado en antibióticos se ha identificado como una opción terapéutica que necesita seguir siendo estudiada. El objetivo de este estudio fue determinar las diferencias en seguridad y eficacia del uso de antibióticos en comparación con la apendicectomía en adultos con apendicitis no complicada. Métodos. Revisión sistemática y metaanálisis. Se encontraron 452 estudios; después de una selección, 45 se evaluaron en texto completo y 15 para calidad metodológica; 11 estudios fueron seleccionados y 9 incluidos en el metaanálisis. Resultados. Se contó con 3186 participantes, de los cuales 1512 fueron tratados con terapia antibiótica y 1674 sometidos a apendicectomía. Se identificó estancia hospitalaria más corta en los pacientes sometidos a apendicectomía (SMD: 0,28; IC95%: 0,14 a 0,41). Para los pacientes tratados con terapia antibiótica, se evidenció puntajes de riesgo menores en las escalas de diagnóstico de apendicitis (SMD: -0,13; IC95%: -0,22 a -0,04), menor éxito terapéutico en un 16 % (RR: 0,84; IC95%: 0,77 a 0,92) y reducción del riesgo de complicaciones del 63 % (RR: 0,37; IC95%: 0,25 a 0,53). Se encontró alta heterogeneidad y riesgo de sesgo de publicación. Conclusiones. La terapia antibiótica necesita mayor evidencia para desenlaces como calidad de vida, satisfacción, dolor, o complicaciones específicas, entre otros, que permitan hacer comparaciones más contundentes. Los pacientes que consideren el manejo conservador necesitan ser adecuadamente asesorados y monitorizados para optimizar sus posibilidades de resultados favorables y la oportuna identificación de complicaciones que necesiten de otros abordajes

Introduction. Acute appendicitis is a frequent surgical emergency, in which conservative antibiotic-based treatment has been identified as a therapeutic option that needs further study. The objective of this study is to determine the differences in safety and efficacy of the use of antibiotics compared to appendectomy in uncomplicated appendicitis in adults. Methods. Systematic review and meta-analysis; 452 studies were found; 45 were evaluated in full text, 15 were evaluated in methodological quality; 11 studies were selected and nine meta-analysed. Results. There were 3186 participants, of whom 1512 were treated with antibiotic therapy and 1674 underwent appendectomy. Shorter stays are identified in patients undergoing appendectomy (SMD: 0.28 CI 95% 0.14 to 0.41). It was evidenced for patients treated with antibiotic therapy lower risk scores in the appendicitis diagnostic scales (SMD: -0.13; CI 95%: -0.22 to -0.04), in 16% less therapeutic success (RR: 0.84; CI 95%: 0.77 to 0.92) and a reduction in the risk of complications of 63% (RR: 0.37, CI 95%: 0.25 to 0.53). High heterogeneity and risk of publication bias were reported.Conclusions. Antibiotic therapy needs more evidence for outcomes such as quality of life, satisfaction, pain, specific complications, among others; that allow for more compelling comparisons. Patients who consider the conservative approach need to be adequately advised and monitored to optimize their chances of favorable results and the timely identification of complications that require other approaches

Factores asociados a la duración de la estancia hospitalaria posterior a la apendicectomía laparoscópica / Factors associated with length of hospital stay after laparoscopic appendectomy

Introducción. El objetivo de este estudio fue determinar los factores asociados a la duración de la estancia hospitalaria posterior a una apendicectomía laparoscópica. Métodos. Se realizó un estudio observacional, analítico, retrospectivo, en el Hospital de Alta Complejidad "Virgen de la Puerta" en Trujillo, Perú, entre 2017 y 2019. La muestra de 78 pacientes se distribuyó en hospitalización prolongada (mayor de 3 días) y hospitalización corta (igual o menor a 3 días). Para el análisis bivariado se emplearon las pruebas t de Student y chi cuadrado y para el análisis multivariado se utilizó regresión logística múltiple. Resultados. No existe asociación entre el recuento de leucocitos y la duración de la hospitalización. El análisis multivariado determinó asociación significativa entre la estancia hospitalaria y las siguientes variables: edad (OR 1,051; p=0,027), tiempo quirúrgico (OR 1,028; p=0,013), diagnóstico quirúrgico de apendicitis complicada (OR 15,008; p=0,018), y sexo femenino (OR 6,079; p=0,010). Conclusión. Los factores asociados a la duración de la hospitalización posterior a apendicectomía laparoscópica en este grupo de pacientes fueron la edad, el tiempo quirúrgico, el diagnóstico quirúrgico de apendicitis complicada y el sexo femenino

Introduction. The objective of this study was to determine factors associated with length of hospital stay after laparoscopic appendectomy. Methods. An observational, analytical, retrospective study was carried out at the "Virgen de la Puerta" High Complexity Hospital in Trujillo, Peru, during the period 2017-2019. The sample of 78 patients was divided into prolonged hospitalization (>3 days) and short hospitalization (≤3 days). For the bivariate analysis, the Student's t-test and chi-square were used. Multiple logistic regression was used for multivariate analysis. Results. There is no association between leukocyte count and length of hospitalization. Multivariate analysis determined a significant association between hospital stay and the following variables: age (OR 1.051; p=0.027), surgical time (OR 1.028; p=0.013), surgical diagnosis of complicated appendicitis (OR 15.008; p=0.018), and female sex (OR 6.079; p=0.010). Conclusion. Factors associated with the duration of hospitalization after laparoscopic appendectomy in these patients were age, surgical time, surgical diagnosis of complicated appendicitis and female sex

Apéndice cecal invertida: hallazgos en colonoscopía / Inverted cecal appendix: colonoscopy findings

Introducción. El apéndice cecal invertido, inversión apendicular o intususcepción apendicular, corresponde a una condición anatómica descrita en 1859. La primera operación de invaginación apendicular se realizó en 1890, y desde entonces se han descrito diferentes técnicas quirúrgicas y endoscópicas para el tratamiento de esta alteración. Casos clínicos. Se presentandos casos de pacientes a quienes se les indicó colonoscopia como parte de estudio de dolor abdominal y diarrea y se identificó una intususcepción apendicular completa y apendicitis y una inversión del muñón apendicular. Resultados. Mediante la colonoscopia se hizo el diagnóstico de apendicitis aguda en una de las pacientes, quien presentaba inversión apendicular completa tipo 5, que fue tratada con manejo farmacológico y seguimiento clínico. En la otra paciente hubo un hallazgo incidental de inversión del muñón apendicular tipo 3. Conclusiones. Durante la realización de estudios colonoscópicos, se debe tener en cuenta el diagnóstico de intususcepción apendicular o apéndice invertido, para evitar intervenciones erróneas, como polipectomías, que generen riesgo potencial en los pacientes.

Introduction. Inverted cecal appendix, appendicular inversion or appendicular intussusception, corresponds to an anatomical condition described in 1859. The first appendicular invagination operation was performed in 1890, and since then different surgical and endoscopic techniques have been described for its treatment. Clinical cases. We present two patients who underwent colonoscopy as part of the study of abdominal pain and diarrhea and in whom were identified a complete appendicular intussusception and appendicitis, and an inversion of the appendicular stump. Results. Through colonoscopy, the diagnosis of acute appendicitis was made in one of the patients, who presented type 5 complete appendicular inversion, which was treated with pharmacological management and clinical follow-up. In the other patient, the incidental finding of inversion of the appendicular stump type 3 was made. Conclusions. During colonoscopy, the diagnosis of appendicular intussusception or inverted appendix must be taken into account to avoid erroneous interventions such as polypectomies that generate potential risk in patients.

Principais Exames Complementares Solicitados para o Diagnóstico das Apendicites Agudas em Adultos em um Hospital do Sul de Santa Catarina / Main complementary exams requested for the diagnosis of acute appendicitis in adults in a hospital in southern Santa Catarina

Introdução: A apendicite aguda exige, na maioria das vezes, um procedimento cirúrgico urgente. Grande parte das pessoas acometidas pela doença apresenta clinicamente sinais e sintomas característicos. Essa doença possui diagnóstico iminentemente clínico, porém podem-se solicitar exames complementares para a elucidação diagnóstica em casos específicos. Quanto à escolha do tratamento, a apendicectomia ainda é a opção principal. Objetivo: Identificar os exames solicitados para o diagnóstico das apendicites operadas nas pessoas adultas no Hospital Nossa Senhora da Conceição, através do Sistema Único de Saúde (SUS), em Tubarão/SC, entre 15 de janeiro e 15 de julho de 2018. Métodos: Trata-se de um estudo epidemiológico observacional com delineamento transversal. Resultados: A média de idade foi de 34,78 anos, sendo a mínima, 18 anos e máxima, 88 anos. A raça mais frequente foi a branca (40 - 66,67%). O sexo predominante foi o masculino (35-58,33%). O local mais escolhido para primeiro atendimento médico foi o HNSC. Entre os pacientes em estudo, 37 obtiveram pontuações entre 7 e 10 na escala de Alvarado. A demora entre o início dos sintomas até a procura por auxílio médico chegou a mais de 7 dias. Foram solicitados, ao todo, 389 exames complementares nas pessoas com suspeita de apendicite, sendo os mais requisitados hemograma, parcial de urina, ultrassonografia, amilase e raio X. Conclusão: Predominaram homens, idade média de aproximadamente 35 anos, raça branca e moradores do município de Tubarão/SC.

Introduction: Acute appendicitis requires, in most cases, an urgent surgical procedure. Most people affected by the disease clinically present characteristic signs and symptoms. This disease has an imminently clinical diagnosis, but complementary tests may be requested for diagnostic elucidation in specific cases. As for the choice of treatment, appendectomy is still the primary choice. Objective: To identify the tests requested for the diagnosis of appendicitis operated on adults at the Hospital Nossa Senhora da Conceição (HNSC), through the Unified Health System (SUS), in Tubarão/SC, between January 15 and July 15, 2018. Methods: This is an observational epidemiological study with a cross-sectional design, and the statistical analysis used the PSPP 1.0.1 software. Results: The mean age was 34.78 years, with the minimum being 18 and the maximum being 88 years. The most frequent race was white (40 - 66.67%). The predominant gender was male (35-58.33%). The most chosen place for first medical attention was the HNSC. Among the patients under study, 37 scored between 7 and 10 on the Alvarado scale. The delay between the onset of symptoms and the search for medical help was more than seven days. The 389 complementary exams were requested for the people with suspected appendicitis, being the most requested hemogram, partial urine test, ultrasonography, amylase, and X-ray. Conclusion: There was a predominance of men, mean age of about 35 years, white, and residents of Tubarão. A total of 389 complementary exams were requested.

Hernia of De Garengeot an up to date of diagnosis, initial management and treatment: a narrative review and a case study report / Hernia de De Garengeot: diagnóstico, manejo inicial y tratamiento actualizados: una revisión narrativa y un informe de estudio de caso

INTRODUCTION A De Garengeot hernia is defined by a femoral hernia containing the appendix. Acute appendicitis within a femoral hernia is an extremely rare surgical presentation and occurs in only 0.08-0.013% of cases cited in the literature and 5 to 15% of all femoral hernias. CASE PRESENTATION A 53-year-old woman presented to the emergency room of our hospital in our ward with acute onset of a right-sided inguinal swelling that occurred earlier that day after performing a heavy lift. Her examination revealed acute appendicitis contained within an incarcerated right femoral hernia. The patient underwent laparoscopic appendectomy with open femoral hernia repair. Intraoperatively, the tip of the appendix was incarcerated within the hernial sac. She was removed through the open inguinal incision after the base of the appendix has been divided laparoscopically. The final pathology showed acute inflamed appendicitis with no evidence of neoplasm. DISCUSSION Physicians should be aware of the rare extent of an unusual presentation of appendicitis such as well as surgical options for treatment. The literature does not conclude on a gold standard for the method of approach. CONCLUSION De Garengeot's hernia remains a rare and unusual surgical presentation of femoral hernia, and the complication of the case by incarceration leading to acute appendicitis provides a challenging surgical approach that should be personalized for each patient

Diverticulitis apendicular, como diagnóstico diferencial / Appendiceal diverticulitis as differential diagnosis

RESUMEN La diverticulitis apendicular (DA) es una patología poco frecuente, considerada clínicamente indistinguible de la apendicitis aguda, aunque podría presentar una sintomatología más leve. Este es el caso de un paciente masculino de 59 años, que concurre al Servicio de Urgencias presentando signos y síntomas sugestivos de una apendicitis aguda; una ecografía informa un asa tubular parcialmente compresible de 7,8 mm de diámetro y una fina banda de líquido laminar, compatible con proceso apendicular agudo. La apendicectomía se realizó de manera convencional evidenciándose un apéndice inflamado principalmente en su región distal. La histología reveló diverticulitis apendicular complicada con rotura. El paciente evolucionó favorablemente y se externó a las 24 horas. Existe una asociación de DA y neoplasia apendicular, por lo que se recomienda una colonoscopia y el seguimiento de este tipo de pacientes.

ABSTRACT Appendiceal diverticulitis (AD) is a rare condition considered clinically identical to acute appendicitis although it may present milder symptoms. We report the case of a 59-year-old male patient who visited the emergency department due to signs and symptoms suggestive of acute appendicitis. An abdominal ultrasound showed partially compressible tubular loop with a diameter of 7.8 mm and a thin band of laminar fluid, consistent with acute appendiceal process. During conventional appendectomy the appendix had signs of inflammation, mainly in the distal region. The histology revealed appendiceal diverticulitis complicated with rupture. The patient had favorable outcome and was discharged 24 hours later. As, there is a clear association between AD and appendiceal neoplasms, colonoscopy and patient monitoring is recommended.

Abordaje laparoscópico de la neoplasia mucinosa apendicular de bajo grado / Laparoscopic approach of low-grade appendiceal mucinous neoplasm

RESUMEN Las neoplasias mucinosas apendiculares son infrecuentes y se clasifican en neoplasias mucinosas de bajo grado, de alto grado y adenocarcinoma mucinoso. Se consideran precursoras del pseudomixoma peritoneal, caracterizado por la acumulación de mucina dentro de la cavidad abdominal. Informamos tres casos de neoplasia mucinosa apendicular de bajo grado, dos varones y una mujer, que presentaron dolor abdominal agudo, diagnosticados preoperatoriamente mediante tomografía y que fueron manejados con un abordaje laparoscópico (apendicectomía, resección parcial de ciego y colectomía derecha, respectivamente). Los tres casos tuvieron una buena evolución posoperatoria y no hubo complicaciones. Se concluye que las neoplasias mucinosas apendiculares son raras y no tienen una presentación clínica específica. El abordaje laparoscópico es una opción segura y factible. La frecuencia y la duración del seguimiento de estos pacientes es motivo de controversia.

ABSTRACT Appendiceal mucinous neoplasms are rare and are classified in low-grade mucinous neoplasm, high-grade mucinous neoplasm and mucinous adenocarcinoma. They are considered precursors of pseudomyxoma peritonei, characterized by the accumulation of mucin within the abdominal cavity. We report three cases of low-grade appendiceal mucinous neoplasm, two men and one woman, who presented with acute abdominal pain. The diagnoses were made preoperatively by computed tomography scan and the tumors were managed through laparoscopic approach (appendectomy, partial resection of the cecum and right colectomy, respectively). The three patients evolved with favorable postoperative outcome without complications. Appendiceal mucinous neoplasms are rare without specific clinical presentation. The laparoscopic approach is a safe and feasible option. The frequency and duration of surveillance in these patients are still controversial.

Simulador de fosa ilíaca derecha para la adquisición de habilidades básicas en apendicectomía convencional / RIGHT ILIAC FOSSA SIMULATOR FOR THE ACQUISITION OF BASIC SKILLS IN CONVENTIONAL APPENDICECTOMY

Introducción: La simulación quirúrgica es un método de enseñanza que cada día va abarcando más terreno, dejando de lado al modelo tradicional de aprendizaje en los servicios de cirugía. El proceso inflamatorio del apéndice cecal es todavía una de las patologías más prevalentes en el área del cirujano general, quien debe tener varias estrategias para poder resolver la misma. Aquí presentamos un simulador de fosa iliaca derecha para la adquisición de habilidades básicas en apendicetomía convencional. Material y Métodos: se desarrolló un simulador de fosa iliaca derecha de la siguiente manera: se recorta el centro la tapa de una caja de aglomerado, y tanto los foamy como el papel crepé en rectángulos del tamaño de la tapa de la caja; se crea un preparado cadavérico utilizando el intestino vacuno; se coloca el preparado y por encima una compresa teñida en la bolsa de polietileno, dentro de la caja; se cierra la caja y se colocan las láminas de foamy y el papel crepé encima de la tapa, fijadas con los tornillos y tuercas, representando la pared abdominal. Resultado: Simulador reproducible, económico y de fácil elaboración. Tiempo total de armado: 1 hora. Conclusiones: Se puede utilizar para simular la técnica quirúrgica de apendicectomía convencional y sus variantes

Introduction: Surgical simulation is a teaching method that covers more ground every day, leaving aside the traditional apprenticeship model in surgery services. The inflammatory process of the cecal appendix is still one of the most prevalent pathologies in the area of the general surgeon, who must have several strategies to solve it. Here we present a right iliac fossa simulator for the acquisition of basic skills in conventional appendectomy. Material and Methods: We cut the center of the lid of the chipboard box, then cut the foamy and the crepe paper into rectangles the size of the lid of the box. We create a cadaveric preparation using the bovine intestine. Then put the preparation with a dyed compress above it in the polyethylene bag, inside the box. We close the box and place on the lid the foamy and crepe paper, fixed with bolts and nuts. Result: Cheap and easy-made simulator. We can armed de simulator in one hour. Conclusions: It can be used to simulate the conventional appendectomy surgical technique and its different variants.

Ultrasonographic findings of child acute appendicitis incorporated into a scoring system

INTRODUCTION@#This study aimed to investigate the ultrasonographic features of paediatric acute appendicitis and incorporate them into a scoring algorithm that will quantify the risk of complications and the strength of recommendation for surgical intervention.@*METHODS@#179 patients with suspected appendicitis who had undergone ultrasonographic examination were included in this study. Based on their medical evaluation and post-surgical histopathological results, patients were categorised into confirmed appendicitis (n = 101) and non-appendicitis (n = 78) groups.@*RESULTS@#In the appendicitis group, the appendix was visualised in 66 (65.3%) patients. In cases where the appendix was not visualised, we looked out for secondary inflammatory signs, which were present in 32 (31.7%) patients. Using stepwise logistic regression, Blumberg's sign, free fluid or collection, hyperaemia, non-compressible appendix and an appendix diameter > 7 mm were found to be significant predictive factors for appendicitis. A new scoring system called POPs was developed, combining inflammatory predictors and ultrasonography findings, with an area under the receiver operating characteristic curve of 0.958 (95% confidence interval 0.929-0.986).@*CONCLUSION@#The newly developed POPs-based diagnosis scheme proved a promising alternative to existing scoring systems such as the Alvarado score. Although further calibration would be beneficial, the proposed scoring scheme is simple and easy to understand, memorise and apply in the emergency room.